Some of Sin City's most hard-boiled citizens cross paths with a few of its more reviled inhabitants.

A runaway train, transporting deadly, toxic chemicals, is barreling down on Stanton, Pennsylvania, and proves to be unstoppable until a veteran engineer and young conductor risk their lives to try and stop it with a switch engine.

A man with a fateful secret embarks on an extraordinary journey of redemption by forever changing the lives of seven strangers.

Jerry and Rachel are two strangers thrown together by a mysterious phone call from a woman they have never met. Threatening their lives and family, she pushes Jerry and Rachel into a series of increasingly dangerous situations, using the technology of everyday life to track and control their every move.

Agent Jay is sent to find Agent Kay and restore his memory after the re-appearance of a case from Kay's past.